Head-to-head review
TrimRX vs Calibrate
TrimRX and Calibrate both compete for patients searching for a GLP-1 weight-loss program. This head-to-head compares pricing, medications, insurance handling, and clinician quality so you can pick the right fit.
Editorial verdict
Calibrate wins on starting price at $138/mo. TrimRX edges ahead on our editorial rating (4.6/5). Choose Calibrate if you want to run brand-name medication through commercial insurance. Pick the program whose medications and care model best match your treatment plan.
Side-by-side comparison
Every attribute scored head-to-head. The highlighted cell is our pick for that row.
TrimRX
4.6 / 5Calibrate
4.0 / 5TrimRX
$249/moCalibrate
$138/moTrimRX
Compounded GLP-1Calibrate
Prescription ProgramTrimRX
- Compounded Semaglutide
- Compounded Tirzepatide
- Oral Semaglutide
Calibrate
- Wegovy
- Zepbound
- Saxenda
- Ozempic
- Mounjaro
TrimRX
47 statesCalibrate
All 50 statesTrimRX
NoCalibrate
YesTrimRX
YesCalibrate
NoTrimRX
YesCalibrate
NoTrimRX
4.6Pharmacist-led compounded GLP-1 with concierge support
TrimRX leans on a pharmacist-first model with a real care team, making it a strong pick for patients new to GLP-1 therapy who want education baked into the program.
Pros
- Dedicated care coach included
- Oral GLP-1 option for needle-averse patients
- Transparent dose-escalation schedule
Cons
- Not available in LA, MS, or AK
- Higher price after 3-month intro period
Calibrate
4.0Year-long metabolic reset with GLP-1 + coaching
Calibrate's 12-month membership pairs brand-name GLP-1 prescribing with intensive 1:1 coaching, and is one of the few programs in the category that consistently publishes outcomes data.
Pros
- Structured 12-month curriculum with 1:1 coaching
- Strong outcomes data published for members
- Insurance navigation for brand-name GLP-1s
Cons
- Annual commitment rather than month-to-month
- Higher upfront cost than à la carte programs
Other head-to-head reviews
Cost, coverage & condition context
Use these resources to pressure-test which program fits your budget, insurance, and clinical situation.
Cost
GLP-1 pricing breakdown
Real monthly cost in every common scenario.
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Insurance
Coverage by insurer
BCBS, UHC, Aetna, Cigna, Kaiser & Medicare matrix.
Open
Condition
GLP-1 for diabetes
When insurers cover Ozempic and Mounjaro.
Open
Condition
GLP-1 for sleep apnea
Zepbound's OSA indication can unlock denials.
Open
By state
GLP-1 in California
Local prescribing rules and licensed programs.
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By state
GLP-1 in Texas
Texas insurance landscape and top brands.
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