Editorial roundup · Updated 2026

Best GLP-1 programs for weight maintenance in 2026

STEP-4 data showed patients who stopped semaglutide regained two-thirds of lost weight within a year. These programs offer maintenance-dose options, structured taper protocols, and ongoing coaching designed for the years after initial weight loss — not just the first six months.

How we picked

We rank programs that explicitly support (1) maintenance dosing below the standard therapeutic ceiling, (2) structured tapers, and (3) coaching for the post-loss phase.

  1. #1 Editor's pick

    Mochi Health

    Obesity-medicine specialists with insurance navigation

    4.7
    $79/mo starting
    • Membership-only model is the cheapest entry point
    • Board-certified obesity medicine physicians
    • Will prescribe non-GLP-1 alternatives when appropriate
    • Medication paid separately
    🎁 Current offer

    $0 first visit

    Category:Prescription ProgramCoverage:All 50 statesInsurance:Accepted

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  2. #2 Top rated

    TrimRX

    Pharmacist-led compounded GLP-1 with concierge support

    4.6
    $249/mo starting
    • Dedicated care coach included
    • Oral GLP-1 option for needle-averse patients
    • Transparent dose-escalation schedule
    • Not available in LA, MS, or AK
    🎁 Current offer

    20% off first 3 months

    Code TRIM20

    Category:Compounded GLP-1Coverage:47 states

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  3. #3 Top rated

    Medvi

    Affordable compounded semaglutide & tirzepatide

    4.5
    $229/mo starting
    • Lowest starting price for compounded GLP-1
    • Free physician consultation
    • No insurance hoops
    • Compounded only — no brand-name Ozempic or Wegovy
    🎁 Current offer

    First month from $149

    Category:Compounded GLP-1Coverage:All 50 states

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  4. #4 Top rated

    Ro (Body)

    Brand-name Wegovy & Zepbound through insurance

    4.4
    $145/mo starting
    • Helps navigate insurance for brand-name GLP-1s
    • Polished mobile app and tracking
    • Access to compounded alternatives if insurance denies
    • Medication cost is separate when using insurance
    🎁 Current offer

    $99 first month

    Category:Telehealth GLP-1Coverage:All 50 statesInsurance:Accepted

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  5. #5 Top rated

    Hims & Hers Weight Loss

    Mass-market GLP-1 access at consumer pricing

    4.3
    $199/mo starting
    • Strong brand and customer service infrastructure
    • Bundled coaching and behavior tools
    • Multiple medication formats
    • Pricing creeps up as dose escalates
    🎁 Current offer

    $149 trial month

    Category:Telehealth GLP-1Coverage:All 50 states

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