Editorial roundup · Updated 2026

Best GLP-1 programs for PCOS in 2026

PCOS is fundamentally an insulin-resistance condition, and GLP-1s address it at the root. These programs stand out for prescribers who track the right labs (fasting insulin, free testosterone, SHBG), combine GLP-1s with metformin when appropriate, and understand fertility considerations.

How we picked

We rank programs with obesity-medicine or hormone-aware clinicians, willingness to layer metformin, and structured cycle / lab tracking for PCOS patients.

  1. #1 Editor's pick

    Mochi Health

    Obesity-medicine specialists with insurance navigation

    4.7
    $79/mo starting
    • Membership-only model is the cheapest entry point
    • Board-certified obesity medicine physicians
    • Will prescribe non-GLP-1 alternatives when appropriate
    • Medication paid separately
    🎁 Current offer

    $0 first visit

    Category:Prescription ProgramCoverage:All 50 statesInsurance:Accepted

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  2. #2 Top rated

    TrimRX

    Pharmacist-led compounded GLP-1 with concierge support

    4.6
    $249/mo starting
    • Dedicated care coach included
    • Oral GLP-1 option for needle-averse patients
    • Transparent dose-escalation schedule
    • Not available in LA, MS, or AK
    🎁 Current offer

    20% off first 3 months

    Code TRIM20

    Category:Compounded GLP-1Coverage:47 states

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  3. #3 Top rated

    Medvi

    Affordable compounded semaglutide & tirzepatide

    4.5
    $229/mo starting
    • Lowest starting price for compounded GLP-1
    • Free physician consultation
    • No insurance hoops
    • Compounded only — no brand-name Ozempic or Wegovy
    🎁 Current offer

    First month from $149

    Category:Compounded GLP-1Coverage:All 50 states

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  4. #4 Top rated

    Ro (Body)

    Brand-name Wegovy & Zepbound through insurance

    4.4
    $145/mo starting
    • Helps navigate insurance for brand-name GLP-1s
    • Polished mobile app and tracking
    • Access to compounded alternatives if insurance denies
    • Medication cost is separate when using insurance
    🎁 Current offer

    $99 first month

    Category:Telehealth GLP-1Coverage:All 50 statesInsurance:Accepted

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