Brand-name medication

Saxenda

Saxenda (liraglutide) is the daily-injection GLP-1 for weight loss — older than Wegovy but still useful when weekly semaglutide isn't tolerated.

Manufacturer
Novo Nordisk
Drug class
GLP-1 receptor agonist
Dose range
0.6 mg → 3.0 mg daily
Average monthly cost
$1,349 without insurance · $25–$75 with most commercial plans
Insurance covered
Often, with prior authorization

Overview

Saxenda is liraglutide dosed at 3.0 mg daily for chronic weight management. It was the first GLP-1 approved for obesity (2014) and remains a useful option for patients who can't tolerate weekly semaglutide or tirzepatide, or who need a shorter-acting medication for tighter side-effect control. Expected weight loss is 5–10% of body weight — meaningfully less than Wegovy or Zepbound.

How it works

Liraglutide is a GLP-1 receptor agonist with a 13-hour half-life. The shorter duration means daily dosing but also means side effects clear faster if a dose is skipped.

Side effects

  • Nausea, especially during the 5-week dose escalation
  • Diarrhea, constipation, vomiting
  • Injection-site reactions
  • Rare: pancreatitis, gallbladder disease, thyroid C-cell tumors (boxed warning)

Who should consider Saxenda

Adults with BMI ≥ 30 (or ≥ 27 with comorbidities) who can't tolerate weekly GLP-1s, prefer a daily routine, or need a shorter-acting agent for surgical or pregnancy planning windows.

Telehealth programs that prescribe Saxenda

Editorial only — not medical advice. Drug pricing and availability change frequently; verify with the prescribing program before relying on any figure on this page.

Other medication guides